Calcium-activated chloride channel regulator 2 (CLCA2)
Homo sapiens — UniProt Q9UQC9
Data last refreshed: (UniProt release unknown)
Key facts
Calcium-activated chloride channel regulator 2 (CLCA2) is a protein from Homo sapiens identified by UniProt accession Q9UQC9, 943 residues long. MolForge cross-references it against 0 known binders and 119 disease associations.
- UniProt accession: Q9UQC9; gene symbol CLCA2.
- Organism: Homo sapiens.
- Length: 943 amino acids.
- Top disease associations (Open Targets): body height, pulse pressure measurement and Hallux valgus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Calcium-activated chloride channel regulator 2 |
|---|---|
| UniProt accession | Q9UQC9 |
| Gene | CLCA2 |
| Organism | Homo sapiens |
| Length | 943 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (119)
Diseases linked to this target (Open Targets).
- body height · score 0.28
- pulse pressure measurement · score 0.21
- Hallux valgus · score 0.21
- body weight · score 0.20
- heart conduction disease · score 0.18
- lean body mass · score 0.18
- glioblastoma multiforme · score 0.18
- breast adenocarcinoma · score 0.16
- appendicular lean mass · score 0.15
- diabetes mellitus · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UQC9-F1 | alphafold | PREDICTED | 86.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UQC9.
Amino-acid sequence (943 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLCA2?
The strongest Open Targets associations for CLCA2 are body height, pulse pressure measurement, Hallux valgus, body weight and heart conduction disease.
How long is the CLCA2 protein?
The Homo sapiens CLCA2 protein (UniProt Q9UQC9) is 943 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UQC9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UQC9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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