Syncytin-1 (ERVW-1)
Homo sapiens — UniProt Q9UQF0
Data last refreshed: (UniProt release unknown)
Key facts
Syncytin-1 (ERVW-1) is a protein from Homo sapiens identified by UniProt accession Q9UQF0, 538 residues long. MolForge cross-references it against 0 known binders and 426 disease associations.
- UniProt accession: Q9UQF0; gene symbol ERVW-1.
- Organism: Homo sapiens.
- Length: 538 amino acids.
- Top disease associations (Open Targets): ulcer disease, heel bone mineral density and infection.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Syncytin-1 |
|---|---|
| UniProt accession | Q9UQF0 |
| Gene | ERVW-1 |
| Organism | Homo sapiens |
| Length | 538 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (426)
Diseases linked to this target (Open Targets).
- ulcer disease · score 0.17
- heel bone mineral density · score 0.13
- infection · score 0.12
- infect · score 0.12
- multiple sclerosis · score 0.11
- neoplasm · score 0.11
- schizophrenia · score 0.11
- bone density · score 0.10
- myeloid sarcoma · score 0.10
- bone quantitative ultrasound measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UQF0-F1 | alphafold | PREDICTED | 59.26 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UQF0.
Amino-acid sequence (538 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ERVW-1?
The strongest Open Targets associations for ERVW-1 are ulcer disease, heel bone mineral density, infection, infect and multiple sclerosis.
How long is the ERVW-1 protein?
The Homo sapiens ERVW-1 protein (UniProt Q9UQF0) is 538 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UQF0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UQF0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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