Protein phosphatase 1 regulatory subunit 3C (PPP1R3C)
Homo sapiens — UniProt Q9UQK1
Data last refreshed: (UniProt release unknown)
Key facts
Protein phosphatase 1 regulatory subunit 3C (PPP1R3C) is a protein from Homo sapiens identified by UniProt accession Q9UQK1, 317 residues long. MolForge cross-references it against 0 known binders and 157 disease associations.
- UniProt accession: Q9UQK1; gene symbol PPP1R3C.
- Organism: Homo sapiens.
- Length: 317 amino acids.
- Top disease associations (Open Targets): disorder of glycogen metabolism, cognitive function measurement and self reported educational attainment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein phosphatase 1 regulatory subunit 3C |
|---|---|
| UniProt accession | Q9UQK1 |
| Gene | PPP1R3C |
| Organism | Homo sapiens |
| Length | 317 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (157)
Diseases linked to this target (Open Targets).
- disorder of glycogen metabolism · score 0.37
- cognitive function measurement · score 0.34
- self reported educational attainment · score 0.31
- smoking behavior · score 0.27
- mitochondrial heteroplasmy measurement · score 0.19
- body height · score 0.18
- intelligence · score 0.16
- head and neck squamous cell carcinoma · score 0.13
- prostate carcinoma · score 0.11
- prostate cancer · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UQK1-F1 | alphafold | PREDICTED | 67.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UQK1.
Amino-acid sequence (317 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PPP1R3C?
The strongest Open Targets associations for PPP1R3C are disorder of glycogen metabolism, cognitive function measurement, self reported educational attainment, smoking behavior and mitochondrial heteroplasmy measurement.
How long is the PPP1R3C protein?
The Homo sapiens PPP1R3C protein (UniProt Q9UQK1) is 317 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UQK1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UQK1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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