Tenascin-N (TNN)
Homo sapiens — UniProt Q9UQP3
Data last refreshed: (UniProt release unknown)
Key facts
Tenascin-N (TNN) is a protein from Homo sapiens identified by UniProt accession Q9UQP3, 1299 residues long. MolForge cross-references it against 0 known binders and 341 disease associations.
- UniProt accession: Q9UQP3; gene symbol TNN.
- Organism: Homo sapiens.
- Length: 1299 amino acids.
- Top disease associations (Open Targets): platelet component distribution width, drug use measurement and bone density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tenascin-N |
|---|---|
| UniProt accession | Q9UQP3 |
| Gene | TNN |
| Organism | Homo sapiens |
| Length | 1299 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (341)
Diseases linked to this target (Open Targets).
- platelet component distribution width · score 0.27
- drug use measurement · score 0.27
- bone density · score 0.26
- urate measurement · score 0.26
- breast adenocarcinoma · score 0.20
- diastolic blood pressure · score 0.11
- Red cell distribution width · score 0.08
- neutrophil count · score 0.07
- Hypomaturation amelogenesis imperfecta · score 0.07
- Hypoplastic amelogenesis imperfecta · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UQP3-F1 | alphafold | PREDICTED | 81.36 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UQP3.
Amino-acid sequence (1299 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TNN?
The strongest Open Targets associations for TNN are platelet component distribution width, drug use measurement, bone density, urate measurement and breast adenocarcinoma.
How long is the TNN protein?
The Homo sapiens TNN protein (UniProt Q9UQP3) is 1299 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UQP3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UQP3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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