Aminopeptidase NAALADL1 (NAALADL1)
Homo sapiens — UniProt Q9UQQ1
Data last refreshed: (UniProt release unknown)
Key facts
Aminopeptidase NAALADL1 (NAALADL1) is a protein from Homo sapiens identified by UniProt accession Q9UQQ1, 740 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q9UQQ1; gene symbol NAALADL1.
- Organism: Homo sapiens.
- Length: 740 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, urate measurement and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Aminopeptidase NAALADL1 |
|---|---|
| UniProt accession | Q9UQQ1 |
| Gene | NAALADL1 |
| Organism | Homo sapiens |
| Length | 740 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.42
- urate measurement · score 0.21
- mean corpuscular volume · score 0.10
- cardiovascular disease · score 0.08
- metabolic syndrome · score 0.06
- Hallux valgus · score 0.05
- neutrophil percentage of leukocytes · score 0.04
- Chagas cardiomyopathy · score 0.04
- Crohn's disease · score 0.04
- gut microbiome measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UQQ1-F1 | alphafold | PREDICTED | 95.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UQQ1.
Amino-acid sequence (740 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NAALADL1?
The strongest Open Targets associations for NAALADL1 are neurodegenerative disease, urate measurement, mean corpuscular volume, cardiovascular disease and metabolic syndrome.
How long is the NAALADL1 protein?
The Homo sapiens NAALADL1 protein (UniProt Q9UQQ1) is 740 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UQQ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UQQ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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