Zinc finger protein 148 (ZNF148)
Homo sapiens — UniProt Q9UQR1
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 148 (ZNF148) is a protein from Homo sapiens identified by UniProt accession Q9UQR1, 794 residues long. MolForge cross-references it against 0 known binders and 187 disease associations.
- UniProt accession: Q9UQR1; gene symbol ZNF148.
- Organism: Homo sapiens.
- Length: 794 amino acids.
- Top disease associations (Open Targets): global developmental delay, absent or hypoplastic corpus callosum, and dysmorphic facies, neurodegenerative disease and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 148 |
|---|---|
| UniProt accession | Q9UQR1 |
| Gene | ZNF148 |
| Organism | Homo sapiens |
| Length | 794 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (187)
Diseases linked to this target (Open Targets).
- global developmental delay, absent or hypoplastic corpus callosum, and dysmorphic facies · score 0.67
- neurodegenerative disease · score 0.52
- genetic disorder · score 0.37
- Neurodevelopmental disorder · score 0.37
- serum albumin measurement · score 0.37
- Intellectual disability · score 0.34
- mean reticulocyte volume · score 0.34
- urate measurement · score 0.32
- vitamin D measurement · score 0.28
- BMI-adjusted waist circumference · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UQR1-F1 | alphafold | PREDICTED | 46.26 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UQR1.
Amino-acid sequence (794 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF148?
The strongest Open Targets associations for ZNF148 are global developmental delay, absent or hypoplastic corpus callosum, and dysmorphic facies, neurodegenerative disease, genetic disorder, Neurodevelopmental disorder and serum albumin measurement.
How long is the ZNF148 protein?
The Homo sapiens ZNF148 protein (UniProt Q9UQR1) is 794 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UQR1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UQR1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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