Lysosome-associated membrane glycoprotein 3 (LAMP3)
Homo sapiens — UniProt Q9UQV4
Data last refreshed: (UniProt release unknown)
Key facts
Lysosome-associated membrane glycoprotein 3 (LAMP3) is a protein from Homo sapiens identified by UniProt accession Q9UQV4, 416 residues long. MolForge cross-references it against 0 known binders and 124 disease associations.
- UniProt accession: Q9UQV4; gene symbol LAMP3.
- Organism: Homo sapiens.
- Length: 416 amino acids.
- Top disease associations (Open Targets): inflammatory bowel disease, Parkinson disease and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Lysosome-associated membrane glycoprotein 3 |
|---|---|
| UniProt accession | Q9UQV4 |
| Gene | LAMP3 |
| Organism | Homo sapiens |
| Length | 416 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (124)
Diseases linked to this target (Open Targets).
- inflammatory bowel disease · score 0.12
- Parkinson disease · score 0.11
- neoplasm · score 0.10
- cancer · score 0.08
- osteosarcoma · score 0.07
- lung carcinoma · score 0.06
- hepatitis B virus infection · score 0.05
- IGA glomerulonephritis · score 0.05
- oral squamous cell carcinoma · score 0.04
- lung adenocarcinoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UQV4-F1 | alphafold | PREDICTED | 67.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UQV4.
Amino-acid sequence (416 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LAMP3?
The strongest Open Targets associations for LAMP3 are inflammatory bowel disease, Parkinson disease, neoplasm, cancer and osteosarcoma.
How long is the LAMP3 protein?
The Homo sapiens LAMP3 protein (UniProt Q9UQV4) is 416 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UQV4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UQV4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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