Cyclin-D-binding Myb-like transcription factor 1 (DMTF1)
Homo sapiens — UniProt Q9Y222
Data last refreshed: (UniProt release unknown)
Key facts
Cyclin-D-binding Myb-like transcription factor 1 (DMTF1) is a protein from Homo sapiens identified by UniProt accession Q9Y222, 760 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q9Y222; gene symbol DMTF1.
- Organism: Homo sapiens.
- Length: 760 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, schizophrenia and sex hormone-binding globulin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cyclin-D-binding Myb-like transcription factor 1 |
|---|---|
| UniProt accession | Q9Y222 |
| Gene | DMTF1 |
| Organism | Homo sapiens |
| Length | 760 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- schizophrenia · score 0.35
- sex hormone-binding globulin measurement · score 0.30
- autism spectrum disorder · score 0.28
- Red cell distribution width · score 0.10
- non-small cell lung carcinoma · score 0.09
- reticulum cell sarcoma · score 0.05
- Ewing sarcoma · score 0.05
- familial atypical multiple mole melanoma syndrome · score 0.04
- neoplasm · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y222-F1 | alphafold | PREDICTED | 52.40 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y222.
Amino-acid sequence (760 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DMTF1?
The strongest Open Targets associations for DMTF1 are neurodegenerative disease, schizophrenia, sex hormone-binding globulin measurement, autism spectrum disorder and Red cell distribution width.
How long is the DMTF1 protein?
The Homo sapiens DMTF1 protein (UniProt Q9Y222) is 760 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y222 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y222 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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