Nucleotide-binding oligomerization domain-containing protein 1 (NOD1)
Homo sapiens — UniProt Q9Y239
Data last refreshed: (UniProt release unknown)
Key facts
Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) is a protein from Homo sapiens identified by UniProt accession Q9Y239, 953 residues long. MolForge cross-references it against 0 known binders and 307 disease associations.
- UniProt accession: Q9Y239; gene symbol NOD1.
- Organism: Homo sapiens.
- Length: 953 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, reticulocyte count and reticulocyte measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nucleotide-binding oligomerization domain-containing protein 1 |
|---|---|
| UniProt accession | Q9Y239 |
| Gene | NOD1 |
| Organism | Homo sapiens |
| Length | 953 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (307)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.45
- reticulocyte count · score 0.43
- reticulocyte measurement · score 0.39
- ferritin measurement · score 0.30
- Immature Reticulocyte Fraction Measurement · score 0.29
- Abnormality of refraction · score 0.29
- myeloid white cell count · score 0.28
- adolescent idiopathic scoliosis · score 0.27
- glioblastoma multiforme · score 0.25
- breast adenocarcinoma · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y239-F1 | alphafold | PREDICTED | 85.71 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y239.
Amino-acid sequence (953 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NOD1?
The strongest Open Targets associations for NOD1 are mean corpuscular volume, reticulocyte count, reticulocyte measurement, ferritin measurement and Immature Reticulocyte Fraction Measurement.
How long is the NOD1 protein?
The Homo sapiens NOD1 protein (UniProt Q9Y239) is 953 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y239 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y239 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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