Small ribosomal subunit protein mS33 (MRPS33)
Homo sapiens — UniProt Q9Y291
Data last refreshed: (UniProt release unknown)
Key facts
Small ribosomal subunit protein mS33 (MRPS33) is a protein from Homo sapiens identified by UniProt accession Q9Y291, 106 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q9Y291; gene symbol MRPS33.
- Organism: Homo sapiens.
- Length: 106 amino acids.
- Top disease associations (Open Targets): bipolar disorder, schizophrenia and attention deficit hyperactivity disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small ribosomal subunit protein mS33 |
|---|---|
| UniProt accession | Q9Y291 |
| Gene | MRPS33 |
| Organism | Homo sapiens |
| Length | 106 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- bipolar disorder · score 0.33
- schizophrenia · score 0.28
- attention deficit hyperactivity disorder · score 0.23
- autism spectrum disorder · score 0.23
- anorexia nervosa · score 0.23
- unipolar depression · score 0.23
- Tourette syndrome · score 0.23
- obsessive-compulsive disorder · score 0.23
- balding measurement · score 0.22
- BMI-adjusted waist circumference · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y291-F1 | alphafold | PREDICTED | 91.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y291.
Amino-acid sequence (106 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPS33?
The strongest Open Targets associations for MRPS33 are bipolar disorder, schizophrenia, attention deficit hyperactivity disorder, autism spectrum disorder and anorexia nervosa.
How long is the MRPS33 protein?
The Homo sapiens MRPS33 protein (UniProt Q9Y291) is 106 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y291 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y291 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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