N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 (B3GNT3)
Homo sapiens — UniProt Q9Y2A9
Data last refreshed: (UniProt release unknown)
Key facts
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 (B3GNT3) is a protein from Homo sapiens identified by UniProt accession Q9Y2A9, 372 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.
- UniProt accession: Q9Y2A9; gene symbol B3GNT3.
- Organism: Homo sapiens.
- Length: 372 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cancer antigen 19.9 measurement and cancer biomarker measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 |
|---|---|
| UniProt accession | Q9Y2A9 |
| Gene | B3GNT3 |
| Organism | Homo sapiens |
| Length | 372 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (60)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- cancer antigen 19.9 measurement · score 0.22
- cancer biomarker measurement · score 0.21
- glioblastoma multiforme · score 0.14
- Parkinson disease · score 0.13
- lung adenocarcinoma · score 0.09
- neoplasm · score 0.08
- pachyonychia congenita · score 0.08
- esophageal squamous cell carcinoma · score 0.05
- non-small cell lung carcinoma · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2A9-F1 | alphafold | PREDICTED | 88.28 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2A9.
Amino-acid sequence (372 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with B3GNT3?
The strongest Open Targets associations for B3GNT3 are neurodegenerative disease, cancer antigen 19.9 measurement, cancer biomarker measurement, glioblastoma multiforme and Parkinson disease.
How long is the B3GNT3 protein?
The Homo sapiens B3GNT3 protein (UniProt Q9Y2A9) is 372 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2A9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2A9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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