TP53-target gene 5 protein (TP53TG5)
Homo sapiens — UniProt Q9Y2B4
Data last refreshed: (UniProt release unknown)
Key facts
TP53-target gene 5 protein (TP53TG5) is a protein from Homo sapiens identified by UniProt accession Q9Y2B4, 290 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.
- UniProt accession: Q9Y2B4; gene symbol TP53TG5.
- Organism: Homo sapiens.
- Length: 290 amino acids.
- Top disease associations (Open Targets): FEV/FVC ratio, gastric adenocarcinoma and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | TP53-target gene 5 protein |
|---|---|
| UniProt accession | Q9Y2B4 |
| Gene | TP53TG5 |
| Organism | Homo sapiens |
| Length | 290 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (6)
Diseases linked to this target (Open Targets).
- FEV/FVC ratio · score 0.18
- gastric adenocarcinoma · score 0.00
- cancer · score 0.00
- neoplasm · score 0.00
- glioblastoma · score 0.00
- relapsing-remitting multiple sclerosis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2B4-F1 | alphafold | PREDICTED | 50.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2B4.
Amino-acid sequence (290 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TP53TG5?
The strongest Open Targets associations for TP53TG5 are FEV/FVC ratio, gastric adenocarcinoma, cancer, neoplasm and glioblastoma.
How long is the TP53TG5 protein?
The Homo sapiens TP53TG5 protein (UniProt Q9Y2B4) is 290 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2B4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2B4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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