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VPS9 domain-containing protein 1 (VPS9D1)

Homo sapiens — UniProt Q9Y2B5

Gene: VPS9D1Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

VPS9 domain-containing protein 1 (VPS9D1) is a protein from Homo sapiens identified by UniProt accession Q9Y2B5, 631 residues long. MolForge cross-references it against 0 known binders and 100 disease associations.

  • UniProt accession: Q9Y2B5; gene symbol VPS9D1.
  • Organism: Homo sapiens.
  • Length: 631 amino acids.
  • Top disease associations (Open Targets): balding measurement, mean corpuscular volume and platelet component distribution width.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameVPS9 domain-containing protein 1
UniProt accessionQ9Y2B5
GeneVPS9D1
OrganismHomo sapiens
Length631 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (100)

Diseases linked to this target (Open Targets).

  • balding measurement · score 0.20
  • mean corpuscular volume · score 0.20
  • platelet component distribution width · score 0.20
  • mean corpuscular hemoglobin concentration · score 0.18
  • monocyte count · score 0.16
  • mean corpuscular hemoglobin · score 0.14
  • hair color · score 0.12
  • melanoma · score 0.11
  • skin pigmentation · score 0.11
  • leukocyte count · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9Y2B5-F1alphafoldPREDICTED75.15—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2B5.

Amino-acid sequence (631 residues)

MAAAAGDGTV KPLQSAMKLA NGAIELDTGN RPREAYTEYL RSIHYISQVL LEEVETTKEA GETVPPDTSK MLKLAQQCLE RAQSTAAKLG KTRLKPTMPA AAPIPQPAGR HRRVYSDEGG KLSPFLPPEI FQKLQGAESQ SCKKELTPLE EASLQNQKLK AAYEARMARL DPSQAMQKTS LTLSLQRQMM ENLVIAKARE ETLQRKMEER RLRLQEAANR RFCSQVALTP EEREQRALYA AILEYEQDHD WPKHWKAKLK RNPGDLSLVT SLVSHLLSLP DHPIAQLLRR LQCSVYSALY PAVSRAAAPA PGCCPPTPNP GSRRLRPSQS LHCMLSPPEP SAAPRPQDSP PTPPLQPGPV GSPSPLGDTA SGLPDKDSSF EDLEQFLGTS ERQGRGRGVQ PEPQLQQLKT AVEEIHNAVD RLLSLTLLAF EGLNTAASKD RCLACIEEPF FSPLWPLLLA LYRSVHRARE AALSRSMELY RNAPPTAIGI PTKLLPQNPE AKGATGYPYC AAAQELGLLV LESCPQKKLE CIVRTLRIIC VCAEDYCPTP EATPQAGPPP IAAAAIGADD LLPILSFVVL RSGLPQLVSE CAALEEFIHE GYLIGEEGYC LTSLQSALSY VELLPRGGLA K

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with VPS9D1?

The strongest Open Targets associations for VPS9D1 are balding measurement, mean corpuscular volume, platelet component distribution width, mean corpuscular hemoglobin concentration and monocyte count.

How long is the VPS9D1 protein?

The Homo sapiens VPS9D1 protein (UniProt Q9Y2B5) is 631 amino acids long.

Browse: Targets: V · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9Y2B5
GeneVPS9D1
OrganismHomo sapiens
Length631
Binders0
Diseases100
View on UniProt