Carbonic anhydrase 5B, mitochondrial (CA5B)

About Carbonic anhydrase 5B, mitochondrial

Carbonic anhydrase 5B, mitochondrial (CA5B) is a protein from Homo sapiens identified by UniProt accession Q9Y2D0, 317 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.

Target properties

Protein name	Carbonic anhydrase 5B, mitochondrial
UniProt accession	Q9Y2D0
Gene	CA5B
Organism	Homo sapiens
Length	317 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (16)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (36)

Diseases linked to this target (Open Targets).

epilepsy · score 0.44
neurodegenerative disease · score 0.21
obstructive sleep apnea · score 0.07
Duchenne muscular dystrophy · score 0.01
osteosarcoma · score 0.01
atrial fibrillation · score 0.01
clostridium difficile infection · score 0.01
cerebral amyloid angiopathy · score 0.01
hypertrophy · score 0.01
allergic rhinitis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y2D0-F1	alphafold	PREDICTED	83.18	—

Amino-acid sequence (317 residues)

MVVMNSLRVI LQASPGKLLW RKFQIPRFMP ARPCSLYTCT YKTRNRALHP LWESVDLVPG GDRQSPINIR WRDSVYDPGL KPLTISYDPA TCLHVWNNGY SFLVEFEDST DKSVIKGGPL EHNYRLKQFH FHWGAIDAWG SEHTVDSKCF PAELHLVHWN AVRFENFEDA ALEENGLAVI GVFLKLGKHH KELQKLVDTL PSIKHKDALV EFGSFDPSCL MPTCPDYWTY SGSLTTPPLS ESVTWIIKKQ PVEVDHDQLE QFRTLLFTSE GEKEKRMVDN FRPLQPLMNR TVRSSFRHDY VLNVQAKPKP ATSQATP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards