Coumarin

Drug profile

Key facts

Coumarin is a drug catalogued in DrugCentral. DrugCentral lists 17 molecular targets, including CA14, SOST and CA6.

• Molecular targets: CA14, SOST, CA6 and CA1 (17 listed in DrugCentral).
• Molecular formula: C9H6O2; molecular weight 146.15 g/mol.

Mechanism & targets

Molecular targets (17)

Target	Gene	Action	Activity
Carbonic anhydrase 14	CA14	unknown	Ki 7.32
Sclerostin	SOST	unknown	Kd 6.64
Carbonic anhydrase 6	CA6	unknown	Ki 5.70
Carbonic anhydrase 1	CA1	unknown	Ki 5.51
Carbonic anhydrase 7	CA7	unknown	Ki 5.48
Induced myeloid leukemia cell differentiation protein Mcl-1	MCL1	unknown	Ki 5.39
Carbonic anhydrase 5B, mitochondrial	CA5B	unknown	Ki 5.28
Carbonic anhydrase 3	CA3	unknown	Ki 5.25
Carbonic anhydrase 4	CA4	unknown	Ki 5.17
Carbonic anhydrase 12	CA12	unknown	Ki 5.05
Carbonic anhydrase 13	Ca13	unknown	Ki 5.04
Carbonic anhydrase 9	CA9	unknown	Ki 5.04
Carbonic anhydrase 2	CA2	unknown	Ki 5.04
Carbonic anhydrase 5A, mitochondrial	CA5A	unknown	Ki 5.03
Amine oxidase [flavin-containing] B	Maob	unknown	IC50 4.92
Carbonic anhydrase 15	Ca15	unknown	Ki 4.40
Amine oxidase [flavin-containing] A	Maoa	unknown	IC50 4.39

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Coumarin is on its molecule page.

• Molecular formula: C₉H₆O₂
• Molecular weight: 146.15 g/mol
• CAS number: 91-64-5
• InChIKey: ZYGHJZDHTFUPRJ-UHFFFAOYSA-N
• PubChem CID: 323

O=C1OC2=CC=CC=C2C=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Coumarin work?

Its molecular targets in DrugCentral include CA14, SOST, CA6 and CA1.

What is the chemical formula of Coumarin?

Coumarin has the molecular formula C9H6O2 and a molecular weight of 146.15 g/mol.

Sources

• DrugCentral drug card 738 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL6466 — compound record and bioactivity
• PubChem CID 323 — chemical identifiers
• DrugBank DB04665 — drug record
• FDA UNII A4VZ22K1WT — substance identity
• UniProt Q9ULX7 (CA14) — target protein
• UniProt Q9BQB4 (SOST) — target protein
• UniProt P23280 (CA6) — target protein
• UniProt P00915 (CA1) — target protein
• UniProt P43166 (CA7) — target protein
• UniProt Q07820 (MCL1) — target protein

How this page is built: methodology · editorial policy & corrections.