Protein EFR3 homolog B (EFR3B)
Homo sapiens — UniProt Q9Y2G0
Data last refreshed: (UniProt release unknown)
Key facts
Protein EFR3 homolog B (EFR3B) is a protein from Homo sapiens identified by UniProt accession Q9Y2G0, 817 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.
- UniProt accession: Q9Y2G0; gene symbol EFR3B.
- Organism: Homo sapiens.
- Length: 817 amino acids.
- Top disease associations (Open Targets): systolic blood pressure, pulse pressure measurement and BMI-adjusted waist-hip ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein EFR3 homolog B |
|---|---|
| UniProt accession | Q9Y2G0 |
| Gene | EFR3B |
| Organism | Homo sapiens |
| Length | 817 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (68)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.39
- pulse pressure measurement · score 0.33
- BMI-adjusted waist-hip ratio · score 0.33
- type 1 diabetes mellitus · score 0.32
- cardiovascular disease · score 0.30
- body weight · score 0.26
- mean arterial pressure · score 0.25
- body fat percentage · score 0.24
- eosinophil count · score 0.21
- waist-hip ratio · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2G0-F1 | alphafold | PREDICTED | 81.77 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2G0.
Amino-acid sequence (817 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EFR3B?
The strongest Open Targets associations for EFR3B are systolic blood pressure, pulse pressure measurement, BMI-adjusted waist-hip ratio, type 1 diabetes mellitus and cardiovascular disease.
How long is the EFR3B protein?
The Homo sapiens EFR3B protein (UniProt Q9Y2G0) is 817 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2G0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2G0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.