Phospholipid-transporting ATPase IF (ATP11B)
Homo sapiens — UniProt Q9Y2G3
Data last refreshed: (UniProt release unknown)
Key facts
Phospholipid-transporting ATPase IF (ATP11B) is a protein from Homo sapiens identified by UniProt accession Q9Y2G3, 1177 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.
- UniProt accession: Q9Y2G3; gene symbol ATP11B.
- Organism: Homo sapiens.
- Length: 1177 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, reticulocyte count and mean corpuscular hemoglobin concentration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Phospholipid-transporting ATPase IF |
|---|---|
| UniProt accession | Q9Y2G3 |
| Gene | ATP11B |
| Organism | Homo sapiens |
| Length | 1177 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (66)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.43
- reticulocyte count · score 0.42
- mean corpuscular hemoglobin concentration · score 0.41
- mean corpuscular hemoglobin · score 0.37
- self reported educational attainment · score 0.36
- reticulocyte measurement · score 0.34
- hair shape measurement · score 0.29
- HbA1c measurement · score 0.28
- chronotype measurement · score 0.27
- body mass index · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2G3-F1 | alphafold | PREDICTED | 81.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2G3.
Amino-acid sequence (1177 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ATP11B?
The strongest Open Targets associations for ATP11B are Red cell distribution width, reticulocyte count, mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin and self reported educational attainment.
How long is the ATP11B protein?
The Homo sapiens ATP11B protein (UniProt Q9Y2G3) is 1177 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2G3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2G3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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