Ankyrin repeat domain-containing protein 6 (ANKRD6)
Homo sapiens — UniProt Q9Y2G4
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat domain-containing protein 6 (ANKRD6) is a protein from Homo sapiens identified by UniProt accession Q9Y2G4, 727 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: Q9Y2G4; gene symbol ANKRD6.
- Organism: Homo sapiens.
- Length: 727 amino acids.
- Top disease associations (Open Targets): lean body mass, Red cell distribution width and body weight.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat domain-containing protein 6 |
|---|---|
| UniProt accession | Q9Y2G4 |
| Gene | ANKRD6 |
| Organism | Homo sapiens |
| Length | 727 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.34
- Red cell distribution width · score 0.32
- body weight · score 0.26
- fat body mass · score 0.24
- body mass index · score 0.20
- coronary artery disease · score 0.20
- whole body water mass · score 0.20
- base metabolic rate measurement · score 0.18
- body fat percentage · score 0.09
- cancer · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2G4-F1 | alphafold | PREDICTED | 70.26 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2G4.
Amino-acid sequence (727 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKRD6?
The strongest Open Targets associations for ANKRD6 are lean body mass, Red cell distribution width, body weight, fat body mass and body mass index.
How long is the ANKRD6 protein?
The Homo sapiens ANKRD6 protein (UniProt Q9Y2G4) is 727 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2G4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2G4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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