Zinc finger protein 30 homolog (ZFP30)
Homo sapiens — UniProt Q9Y2G7
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 30 homolog (ZFP30) is a protein from Homo sapiens identified by UniProt accession Q9Y2G7, 519 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q9Y2G7; gene symbol ZFP30.
- Organism: Homo sapiens.
- Length: 519 amino acids.
- Top disease associations (Open Targets): FEV/FVC ratio, Rare genetic intellectual disability with developmental anomaly and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 30 homolog |
|---|---|
| UniProt accession | Q9Y2G7 |
| Gene | ZFP30 |
| Organism | Homo sapiens |
| Length | 519 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- FEV/FVC ratio · score 0.33
- Rare genetic intellectual disability with developmental anomaly · score 0.27
- neurodegenerative disease · score 0.26
- sex hormone-binding globulin measurement · score 0.11
- serum gamma-glutamyl transferase measurement · score 0.09
- glomerular filtration rate · score 0.08
- cystatin C measurement · score 0.06
- C-reactive protein measurement · score 0.06
- bilirubin measurement · score 0.05
- creatinine measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2G7-F1 | alphafold | PREDICTED | 72.45 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2G7.
Amino-acid sequence (519 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZFP30?
The strongest Open Targets associations for ZFP30 are FEV/FVC ratio, Rare genetic intellectual disability with developmental anomaly, neurodegenerative disease, sex hormone-binding globulin measurement and serum gamma-glutamyl transferase measurement.
How long is the ZFP30 protein?
The Homo sapiens ZFP30 protein (UniProt Q9Y2G7) is 519 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2G7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2G7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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