DnaJ homolog subfamily C member 16 (DNAJC16)
Homo sapiens — UniProt Q9Y2G8
Data last refreshed: (UniProt release unknown)
Key facts
DnaJ homolog subfamily C member 16 (DNAJC16) is a protein from Homo sapiens identified by UniProt accession Q9Y2G8, 782 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q9Y2G8; gene symbol DNAJC16.
- Organism: Homo sapiens.
- Length: 782 amino acids.
- Top disease associations (Open Targets): glomerular filtration rate, creatinine measurement and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DnaJ homolog subfamily C member 16 |
|---|---|
| UniProt accession | Q9Y2G8 |
| Gene | DNAJC16 |
| Organism | Homo sapiens |
| Length | 782 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- glomerular filtration rate · score 0.25
- creatinine measurement · score 0.24
- urate measurement · score 0.24
- cystatin C measurement · score 0.19
- urinary metabolite measurement · score 0.19
- hereditary spastic paraplegia · score 0.19
- erythrocyte count · score 0.15
- hemoglobin measurement · score 0.12
- hematocrit · score 0.12
- serum metabolite measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2G8-F1 | alphafold | PREDICTED | 77.45 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2G8.
Amino-acid sequence (782 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DNAJC16?
The strongest Open Targets associations for DNAJC16 are glomerular filtration rate, creatinine measurement, urate measurement, cystatin C measurement and urinary metabolite measurement.
How long is the DNAJC16 protein?
The Homo sapiens DNAJC16 protein (UniProt Q9Y2G8) is 782 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2G8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2G8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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