Disks large-associated protein 4 (DLGAP4)
Homo sapiens — UniProt Q9Y2H0
Data last refreshed: (UniProt release unknown)
Key facts
Disks large-associated protein 4 (DLGAP4) is a protein from Homo sapiens identified by UniProt accession Q9Y2H0, 992 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.
- UniProt accession: Q9Y2H0; gene symbol DLGAP4.
- Organism: Homo sapiens.
- Length: 992 amino acids.
- Top disease associations (Open Targets): non-melanoma skin carcinoma, hair colour measurement and diastolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Disks large-associated protein 4 |
|---|---|
| UniProt accession | Q9Y2H0 |
| Gene | DLGAP4 |
| Organism | Homo sapiens |
| Length | 992 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (66)
Diseases linked to this target (Open Targets).
- non-melanoma skin carcinoma · score 0.32
- hair colour measurement · score 0.30
- diastolic blood pressure · score 0.19
- hepatocellular carcinoma · score 0.08
- sunburn · score 0.07
- hair color · score 0.06
- skin pigmentation · score 0.05
- body height · score 0.04
- basal cell carcinoma · score 0.04
- gonorrhea · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2H0-F1 | alphafold | PREDICTED | 49.45 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2H0.
Amino-acid sequence (992 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DLGAP4?
The strongest Open Targets associations for DLGAP4 are non-melanoma skin carcinoma, hair colour measurement, diastolic blood pressure, hepatocellular carcinoma and sunburn.
How long is the DLGAP4 protein?
The Homo sapiens DLGAP4 protein (UniProt Q9Y2H0) is 992 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2H0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2H0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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