Serine/threonine-protein kinase 38-like (STK38L)
Homo sapiens — UniProt Q9Y2H1
Data last refreshed: (UniProt release unknown)
Key facts
Serine/threonine-protein kinase 38-like (STK38L) is a protein from Homo sapiens identified by UniProt accession Q9Y2H1, 464 residues long. MolForge cross-references it against 1 known binders and 59 disease associations.
- UniProt accession: Q9Y2H1; gene symbol STK38L.
- Organism: Homo sapiens.
- Length: 464 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, neurodegenerative disease and Parkinson disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine/threonine-protein kinase 38-like |
|---|---|
| UniProt accession | Q9Y2H1 |
| Gene | STK38L |
| Organism | Homo sapiens |
| Length | 464 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (59)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.36
- neurodegenerative disease · score 0.27
- Parkinson disease · score 0.27
- lysosomal storage disease · score 0.27
- multiple sclerosis · score 0.27
- Alzheimer disease · score 0.27
- metabolite measurement · score 0.26
- glioma · score 0.24
- neutrophil count · score 0.23
- myeloid white cell count · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2H1-F1 | alphafold | PREDICTED | 84.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2H1.
Amino-acid sequence (464 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with STK38L?
The strongest Open Targets associations for STK38L are self reported educational attainment, neurodegenerative disease, Parkinson disease, lysosomal storage disease and multiple sclerosis.
How long is the STK38L protein?
The Homo sapiens STK38L protein (UniProt Q9Y2H1) is 464 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2H1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2H1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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