Fibronectin type-III domain-containing protein 3A (FNDC3A)
Homo sapiens — UniProt Q9Y2H6
Data last refreshed: (UniProt release unknown)
Key facts
Fibronectin type-III domain-containing protein 3A (FNDC3A) is a protein from Homo sapiens identified by UniProt accession Q9Y2H6, 1198 residues long. MolForge cross-references it against 0 known binders and 139 disease associations.
- UniProt accession: Q9Y2H6; gene symbol FNDC3A.
- Organism: Homo sapiens.
- Length: 1198 amino acids.
- Top disease associations (Open Targets): leukocyte count, cystatin C measurement and neutrophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Fibronectin type-III domain-containing protein 3A |
|---|---|
| UniProt accession | Q9Y2H6 |
| Gene | FNDC3A |
| Organism | Homo sapiens |
| Length | 1198 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (139)
Diseases linked to this target (Open Targets).
- leukocyte count · score 0.34
- cystatin C measurement · score 0.33
- neutrophil count · score 0.32
- apolipoprotein A 1 measurement · score 0.30
- high density lipoprotein cholesterol measurement · score 0.30
- age at menarche · score 0.30
- electrocardiography · score 0.23
- body height · score 0.21
- myeloid white cell count · score 0.21
- insulin like growth factor measurement · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2H6-F1 | alphafold | PREDICTED | 77.68 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2H6.
Amino-acid sequence (1198 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FNDC3A?
The strongest Open Targets associations for FNDC3A are leukocyte count, cystatin C measurement, neutrophil count, apolipoprotein A 1 measurement and high density lipoprotein cholesterol measurement.
How long is the FNDC3A protein?
The Homo sapiens FNDC3A protein (UniProt Q9Y2H6) is 1198 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2H6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2H6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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