Netrin-G1 (NTNG1)
Homo sapiens — UniProt Q9Y2I2
Data last refreshed: (UniProt release unknown)
Key facts
Netrin-G1 (NTNG1) is a protein from Homo sapiens identified by UniProt accession Q9Y2I2, 539 residues long. MolForge cross-references it against 0 known binders and 92 disease associations.
- UniProt accession: Q9Y2I2; gene symbol NTNG1.
- Organism: Homo sapiens.
- Length: 539 amino acids.
- Top disease associations (Open Targets): body mass index, lean body mass and body weight.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Netrin-G1 |
|---|---|
| UniProt accession | Q9Y2I2 |
| Gene | NTNG1 |
| Organism | Homo sapiens |
| Length | 539 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (92)
Diseases linked to this target (Open Targets).
- body mass index · score 0.45
- lean body mass · score 0.43
- body weight · score 0.42
- complex neurodevelopmental disorder · score 0.37
- atypical Rett syndrome · score 0.37
- blood protein measurement · score 0.37
- fat body mass · score 0.37
- leukocyte count · score 0.32
- waist circumference · score 0.29
- base metabolic rate measurement · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2I2-F1 | alphafold | PREDICTED | 83.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2I2.
Amino-acid sequence (539 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NTNG1?
The strongest Open Targets associations for NTNG1 are body mass index, lean body mass, body weight, complex neurodevelopmental disorder and atypical Rett syndrome.
How long is the NTNG1 protein?
The Homo sapiens NTNG1 protein (UniProt Q9Y2I2) is 539 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2I2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2I2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.