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Ninein-like protein (NINL)

Homo sapiens — UniProt Q9Y2I6

Gene: NINLHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Ninein-like protein (NINL) is a protein from Homo sapiens identified by UniProt accession Q9Y2I6, 1382 residues long. MolForge cross-references it against 0 known binders and 110 disease associations.

  • UniProt accession: Q9Y2I6; gene symbol NINL.
  • Organism: Homo sapiens.
  • Length: 1382 amino acids.
  • Top disease associations (Open Targets): platelet count, ovarian cancer and breast adenocarcinoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameNinein-like protein
UniProt accessionQ9Y2I6
GeneNINL
OrganismHomo sapiens
Length1382 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (110)

Diseases linked to this target (Open Targets).

  • platelet count · score 0.38
  • ovarian cancer · score 0.23
  • breast adenocarcinoma · score 0.23
  • urate measurement · score 0.22
  • hemoglobin measurement · score 0.21
  • hematocrit · score 0.21
  • forced expiratory volume · score 0.20
  • mean corpuscular volume · score 0.18
  • diet measurement · score 0.17
  • mean corpuscular hemoglobin concentration · score 0.17

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9Y2I6-F1alphafoldPREDICTED65.68—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2I6.

Amino-acid sequence (1382 residues)

MDEEENHYVS QLREVYSSCD TTGTGFLDRQ ELTQLCLKLH LEQQLPVLLQ TLLGNDHFAR VNFEEFKEGF VAVLSSNAGV RPSDEDSSSL ESAASSAIPP KYVNGSKWYG RRSRPELCDA ATEARRVPEQ QTQASLKSHL WRSASLESVE SPKSDEEAES TKEAQNELFE AQGQLQTWDS EDFGSPQKSC SPSFDTPESQ IRGVWEELGV GSSGHLSEQE LAVVCQSVGL QGLEKEELED LFNKLDQDGD GKVSLEEFQL GLFSHEPALL LESSTRVKPS KAWSHYQVPE ESGCHTTTTS SLVSLCSSLR LFSSIDDGSG FAFPDQVLAM WTQEGIQNGR EILQSLDFSV DEKVNLLELT WALDNELMTV DSAVQQAALA CYHQELSYQQ GQVEQLARER DKARQDLERA EKRNLEFVKE MDDCHSTLEQ LTEKKIKHLE QGYRERLSLL RSEVEAEREL FWEQAHRQRA ALEWDVGRLQ AEEAGLREKL TLALKENSRL QKEIVEVVEK LSDSERLALK LQKDLEFVLK DKLEPQSAEL LAQEERFAAV LKEYELKCRD LQDRNDELQA ELEGLWARLP KNRHSPSWSP DGRRRQLPGL GPAGISFLGN SAPVSIETEL MMEQVKEHYQ DLRTQLETKV NYYEREIAAL KRNFEKERKD MEQARRREVS VLEGQKADLE ELHEKSQEVI WGLQEQLQDT ARGPEPEQMG LAPCCTQALC GLALRHHSHL QQIRREAEAE LSGELSGLGA LPARRDLTLE LEEPPQGPLP RGSQRSEQLE LERALKLQPC ASEKRAQMCV SLALEEEELE LARGKRVDGP SLEAEMQALP KDGLVAGSGQ EGTRGLLPLR PGCGERPLAW LAPGDGRESE EAAGAGPRRR QAQDTEATQS PAPAPAPASH GPSERWSRMQ PCGVDGDIVP KEPEPFGASA AGLEQPGARE LPLLGTERDA SQTQPRMWEP PLRPAASCRG QAERLQAIQE ERARSWSRGT QEQASEQQAR AEGALEPGCH KHSVEVARRG SLPSHLQLAD PQGSWQEQLA APEEGETKIA LEREKDDMET KLLHLEDVVR ALEKHVDLRE NDRLEFHRLS EENTLLKNDL GRVRQELEAA ESTHDAQRKE IEVLKKDKEK ACSEMEVLNR QNQNYKDQLS QLNVRVLQLG QEASTHQAQN EEHRVTIQML TQSLEEVVRS GQQQSDQIQK LRVELECLNQ EHQSLQLPWS ELTQTLEESQ DQVQGAHLRL RQAQAQHLQE VRLVPQDRVA ELHRLLSLQG EQARRRLDAQ REEHEKQLKA TEERVEEAEM ILKNMEMLLQ EKVDKLKEQF EKNTKSDLLL KELYVENAHL VRALQATEEK QRGAEKQSRL LEEKVRALNK LVSRIAPAAL SV

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with NINL?

The strongest Open Targets associations for NINL are platelet count, ovarian cancer, breast adenocarcinoma, urate measurement and hemoglobin measurement.

How long is the NINL protein?

The Homo sapiens NINL protein (UniProt Q9Y2I6) is 1382 amino acids long.

Browse: Targets: N · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9Y2I6
GeneNINL
OrganismHomo sapiens
Length1382
Binders0
Diseases110
View on UniProt