WD repeat-containing protein 37 (WDR37)
Homo sapiens — UniProt Q9Y2I8
Data last refreshed: (UniProt release unknown)
Key facts
WD repeat-containing protein 37 (WDR37) is a protein from Homo sapiens identified by UniProt accession Q9Y2I8, 494 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.
- UniProt accession: Q9Y2I8; gene symbol WDR37.
- Organism: Homo sapiens.
- Length: 494 amino acids.
- Top disease associations (Open Targets): neurooculocardiogenitourinary syndrome, Intellectual disability and coloboma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | WD repeat-containing protein 37 |
|---|---|
| UniProt accession | Q9Y2I8 |
| Gene | WDR37 |
| Organism | Homo sapiens |
| Length | 494 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (55)
Diseases linked to this target (Open Targets).
- neurooculocardiogenitourinary syndrome · score 0.72
- Intellectual disability · score 0.56
- coloboma · score 0.47
- Global developmental delay · score 0.46
- Seizure · score 0.46
- Abnormality of the skeletal system · score 0.46
- Hearing abnormality · score 0.46
- disease of genitourinary system · score 0.46
- Abnormality of the eye · score 0.46
- Abnormality of the cardiovascular system · score 0.46
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2I8-F1 | alphafold | PREDICTED | 78.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2I8.
Amino-acid sequence (494 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WDR37?
The strongest Open Targets associations for WDR37 are neurooculocardiogenitourinary syndrome, Intellectual disability, coloboma, Global developmental delay and Seizure.
How long is the WDR37 protein?
The Homo sapiens WDR37 protein (UniProt Q9Y2I8) is 494 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2I8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2I8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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