R3H domain-containing protein 2 (R3HDM2)
Homo sapiens — UniProt Q9Y2K5
Data last refreshed: (UniProt release unknown)
Key facts
R3H domain-containing protein 2 (R3HDM2) is a protein from Homo sapiens identified by UniProt accession Q9Y2K5, 976 residues long. MolForge cross-references it against 0 known binders and 58 disease associations.
- UniProt accession: Q9Y2K5; gene symbol R3HDM2.
- Organism: Homo sapiens.
- Length: 976 amino acids.
- Top disease associations (Open Targets): glomerular filtration rate, erythrocyte count and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | R3H domain-containing protein 2 |
|---|---|
| UniProt accession | Q9Y2K5 |
| Gene | R3HDM2 |
| Organism | Homo sapiens |
| Length | 976 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (58)
Diseases linked to this target (Open Targets).
- glomerular filtration rate · score 0.24
- erythrocyte count · score 0.24
- urate measurement · score 0.23
- cystatin C measurement · score 0.23
- sex hormone-binding globulin measurement · score 0.23
- apolipoprotein A 1 measurement · score 0.22
- triglyceride measurement · score 0.22
- creatinine measurement · score 0.21
- testosterone measurement · score 0.19
- high density lipoprotein cholesterol measurement · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2K5-F1 | alphafold | PREDICTED | 48.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2K5.
Amino-acid sequence (976 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with R3HDM2?
The strongest Open Targets associations for R3HDM2 are glomerular filtration rate, erythrocyte count, urate measurement, cystatin C measurement and sex hormone-binding globulin measurement.
How long is the R3HDM2 protein?
The Homo sapiens R3HDM2 protein (UniProt Q9Y2K5) is 976 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2K5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2K5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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