Syntaxin-binding protein 5-like (STXBP5L)
Homo sapiens — UniProt Q9Y2K9
Data last refreshed: (UniProt release unknown)
Key facts
Syntaxin-binding protein 5-like (STXBP5L) is a protein from Homo sapiens identified by UniProt accession Q9Y2K9, 1186 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q9Y2K9; gene symbol STXBP5L.
- Organism: Homo sapiens.
- Length: 1186 amino acids.
- Top disease associations (Open Targets): cutaneous mastocytosis, non-small cell lung carcinoma and lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Syntaxin-binding protein 5-like |
|---|---|
| UniProt accession | Q9Y2K9 |
| Gene | STXBP5L |
| Organism | Homo sapiens |
| Length | 1186 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- cutaneous mastocytosis · score 0.10
- non-small cell lung carcinoma · score 0.04
- lung carcinoma · score 0.04
- attention deficit hyperactivity disorder · score 0.04
- atypical teratoid rhabdoid tumor · score 0.04
- schizophrenia 15 · score 0.03
- Glanzmann thrombasthenia 1 · score 0.03
- Phelan-McDermid syndrome · score 0.03
- glioblastoma multiforme · score 0.03
- primitive neuroectodermal tumor · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2K9-F1 | alphafold | PREDICTED | 76.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2K9.
Amino-acid sequence (1186 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with STXBP5L?
The strongest Open Targets associations for STXBP5L are cutaneous mastocytosis, non-small cell lung carcinoma, lung carcinoma, attention deficit hyperactivity disorder and atypical teratoid rhabdoid tumor.
How long is the STXBP5L protein?
The Homo sapiens STXBP5L protein (UniProt Q9Y2K9) is 1186 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2K9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2K9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.