Zinc finger protein with KRAB and SCAN domains 5 (ZKSCAN5)
Homo sapiens — UniProt Q9Y2L8
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein with KRAB and SCAN domains 5 (ZKSCAN5) is a protein from Homo sapiens identified by UniProt accession Q9Y2L8, 839 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.
- UniProt accession: Q9Y2L8; gene symbol ZKSCAN5.
- Organism: Homo sapiens.
- Length: 839 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mean corpuscular volume and dehydroepiandrosterone sulphate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein with KRAB and SCAN domains 5 |
|---|---|
| UniProt accession | Q9Y2L8 |
| Gene | ZKSCAN5 |
| Organism | Homo sapiens |
| Length | 839 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (52)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- mean corpuscular volume · score 0.24
- dehydroepiandrosterone sulphate measurement · score 0.18
- myeloid white cell count · score 0.13
- hormone measurement · score 0.11
- body mass index · score 0.11
- urinary metabolite measurement · score 0.11
- blood metabolite measurement · score 0.09
- progesterone measurement · score 0.08
- serum metabolite measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2L8-F1 | alphafold | PREDICTED | 57.99 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2L8.
Amino-acid sequence (839 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZKSCAN5?
The strongest Open Targets associations for ZKSCAN5 are neurodegenerative disease, mean corpuscular volume, dehydroepiandrosterone sulphate measurement, myeloid white cell count and hormone measurement.
How long is the ZKSCAN5 protein?
The Homo sapiens ZKSCAN5 protein (UniProt Q9Y2L8) is 839 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2L8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2L8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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