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Long-chain fatty acid transport protein 5 (SLC27A5)

Homo sapiens — UniProt Q9Y2P5

Gene: SLC27A5Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Long-chain fatty acid transport protein 5 (SLC27A5) is a protein from Homo sapiens identified by UniProt accession Q9Y2P5, 690 residues long. MolForge cross-references it against 0 known binders and 125 disease associations.

  • UniProt accession: Q9Y2P5; gene symbol SLC27A5.
  • Organism: Homo sapiens.
  • Length: 690 amino acids.
  • Top disease associations (Open Targets): sex hormone-binding globulin measurement, mean platelet volume and cutaneous melanoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameLong-chain fatty acid transport protein 5
UniProt accessionQ9Y2P5
GeneSLC27A5
OrganismHomo sapiens
Length690 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (125)

Diseases linked to this target (Open Targets).

  • sex hormone-binding globulin measurement · score 0.34
  • mean platelet volume · score 0.20
  • cutaneous melanoma · score 0.15
  • heel bone mineral density · score 0.14
  • colorectal cancer · score 0.12
  • hepatocellular carcinoma · score 0.11
  • colorectal adenoma · score 0.11
  • myoepithelial tumor · score 0.11
  • low density lipoprotein cholesterol measurement · score 0.11
  • neoplasm · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9Y2P5-F1alphafoldPREDICTED86.06—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2P5.

Amino-acid sequence (690 residues)

MGVRQQLALL LLLLLLLWGL GQPVWPVAVA LTLRWLLGDP TCCVLLGLAM LARPWLGPWV PHGLSLAAAA LALTLLPARL PPGLRWLPAD VIFLAKILHL GLKIRGCLSR QPPDTFVDAF ERRARAQPGR ALLVWTGPGA GSVTFGELDA RACQAAWALK AELGDPASLC AGEPTALLVL ASQAVPALCM WLGLAKLGCP TAWINPHGRG MPLAHSVLSS GARVLVVDPD LRESLEEILP KLQAENIRCF YLSHTSPTPG VGALGAALDA APSHPVPADL RAGITWRSPA LFIYTSGTTG LPKPAILTHE RVLQMSKMLS LSGATADDVV YTVLPLYHVM GLVVGILGCL DLGATCVLAP KFSTSCFWDD CRQHGVTVIL YVGELLRYLC NIPQQPEDRT HTVRLAMGNG LRADVWETFQ QRFGPIRIWE VYGSTEGNMG LVNYVGRCGA LGKMSCLLRM LSPFELVQFD MEAAEPVRDN QGFCIPVGLG EPGLLLTKVV SQQPFVGYRG PRELSERKLV RNVRQSGDVY YNTGDVLAMD REGFLYFRDR LGDTFRWKGE NVSTHEVEGV LSQVDFLQQV NVYGVCVPGC EGKVGMAAVQ LAPGQTFDGE KLYQHVRAWL PAYATPHFIR IQDAMEVTST FKLMKTRLVR EGFNVGIVVD PLFVLDNRAQ SFRPLTAEMY QAVCEGTWRL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SLC27A5?

The strongest Open Targets associations for SLC27A5 are sex hormone-binding globulin measurement, mean platelet volume, cutaneous melanoma, heel bone mineral density and colorectal cancer.

How long is the SLC27A5 protein?

The Homo sapiens SLC27A5 protein (UniProt Q9Y2P5) is 690 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9Y2P5
GeneSLC27A5
OrganismHomo sapiens
Length690
Binders0
Diseases125
View on UniProt