Zinc finger protein 257 (ZNF257)
Homo sapiens — UniProt Q9Y2Q1
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 257 (ZNF257) is a protein from Homo sapiens identified by UniProt accession Q9Y2Q1, 563 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q9Y2Q1; gene symbol ZNF257.
- Organism: Homo sapiens.
- Length: 563 amino acids.
- Top disease associations (Open Targets): Testicular Germ Cell Tumor, telomere length and benign neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 257 |
|---|---|
| UniProt accession | Q9Y2Q1 |
| Gene | ZNF257 |
| Organism | Homo sapiens |
| Length | 563 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- Testicular Germ Cell Tumor · score 0.16
- telomere length · score 0.15
- benign neoplasm · score 0.14
- uterine fibroid · score 0.12
- Down syndrome · score 0.07
- type 2 diabetes mellitus · score 0.07
- cystatin C measurement · score 0.05
- lymphocyte count · score 0.05
- systolic blood pressure · score 0.05
- Drugs used in diabetes use measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2Q1-F1 | alphafold | PREDICTED | 67.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2Q1.
Amino-acid sequence (563 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF257?
The strongest Open Targets associations for ZNF257 are Testicular Germ Cell Tumor, telomere length, benign neoplasm, uterine fibroid and Down syndrome.
How long is the ZNF257 protein?
The Homo sapiens ZNF257 protein (UniProt Q9Y2Q1) is 563 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2Q1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2Q1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.