Small ribosomal subunit protein bS1m (MRPS28)
Homo sapiens — UniProt Q9Y2Q9
Data last refreshed: (UniProt release unknown)
Key facts
Small ribosomal subunit protein bS1m (MRPS28) is a protein from Homo sapiens identified by UniProt accession Q9Y2Q9, 187 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q9Y2Q9; gene symbol MRPS28.
- Organism: Homo sapiens.
- Length: 187 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, combined oxidative phosphorylation deficiency 47 and heel bone mineral density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small ribosomal subunit protein bS1m |
|---|---|
| UniProt accession | Q9Y2Q9 |
| Gene | MRPS28 |
| Organism | Homo sapiens |
| Length | 187 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- combined oxidative phosphorylation deficiency 47 · score 0.45
- heel bone mineral density · score 0.28
- visual perception measurement · score 0.24
- bone quantitative ultrasound measurement · score 0.24
- electrocardiography · score 0.20
- cortical thickness · score 0.15
- drug use measurement · score 0.10
- eosinophil count · score 0.08
- drug-induced liver injury · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2Q9-F1 | alphafold | PREDICTED | 77.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2Q9.
Amino-acid sequence (187 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPS28?
The strongest Open Targets associations for MRPS28 are neurodegenerative disease, combined oxidative phosphorylation deficiency 47, heel bone mineral density, visual perception measurement and bone quantitative ultrasound measurement.
How long is the MRPS28 protein?
The Homo sapiens MRPS28 protein (UniProt Q9Y2Q9) is 187 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2Q9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2Q9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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