Small ribosomal subunit protein uS17m (MRPS17)
Homo sapiens — UniProt Q9Y2R5
Data last refreshed: (UniProt release unknown)
Key facts
Small ribosomal subunit protein uS17m (MRPS17) is a protein from Homo sapiens identified by UniProt accession Q9Y2R5, 130 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q9Y2R5; gene symbol MRPS17.
- Organism: Homo sapiens.
- Length: 130 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Alzheimer disease and lysosomal storage disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small ribosomal subunit protein uS17m |
|---|---|
| UniProt accession | Q9Y2R5 |
| Gene | MRPS17 |
| Organism | Homo sapiens |
| Length | 130 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.43
- Alzheimer disease · score 0.33
- lysosomal storage disease · score 0.33
- Parkinson disease · score 0.33
- multiple sclerosis · score 0.33
- insulin like growth factor measurement · score 0.20
- neutrophil count · score 0.16
- myeloid white cell count · score 0.14
- leukocyte count · score 0.13
- serum alanine aminotransferase measurement · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2R5-F1 | alphafold | PREDICTED | 92.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2R5.
Amino-acid sequence (130 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPS17?
The strongest Open Targets associations for MRPS17 are neurodegenerative disease, Alzheimer disease, lysosomal storage disease, Parkinson disease and multiple sclerosis.
How long is the MRPS17 protein?
The Homo sapiens MRPS17 protein (UniProt Q9Y2R5) is 130 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2R5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2R5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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