Small ribosomal subunit protein uS7m (MRPS7)
Homo sapiens — UniProt Q9Y2R9
Data last refreshed: (UniProt release unknown)
Key facts
Small ribosomal subunit protein uS7m (MRPS7) is a protein from Homo sapiens identified by UniProt accession Q9Y2R9, 242 residues long. MolForge cross-references it against 0 known binders and 141 disease associations.
- UniProt accession: Q9Y2R9; gene symbol MRPS7.
- Organism: Homo sapiens.
- Length: 242 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, combined oxidative phosphorylation deficiency 34 and Sensorineural hearing impairment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small ribosomal subunit protein uS7m |
|---|---|
| UniProt accession | Q9Y2R9 |
| Gene | MRPS7 |
| Organism | Homo sapiens |
| Length | 242 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (141)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- combined oxidative phosphorylation deficiency 34 · score 0.50
- Sensorineural hearing impairment · score 0.33
- Premature ovarian insufficiency · score 0.33
- sensorineural hearing loss · score 0.33
- Alzheimer disease · score 0.26
- lysosomal storage disease · score 0.26
- Parkinson disease · score 0.26
- multiple sclerosis · score 0.26
- testosterone measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2R9-F1 | alphafold | PREDICTED | 86.83 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2R9.
Amino-acid sequence (242 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPS7?
The strongest Open Targets associations for MRPS7 are neurodegenerative disease, combined oxidative phosphorylation deficiency 34, Sensorineural hearing impairment, Premature ovarian insufficiency and sensorineural hearing loss.
How long is the MRPS7 protein?
The Homo sapiens MRPS7 protein (UniProt Q9Y2R9) is 242 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2R9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2R9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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