Translation machinery-associated protein 7 (TMA7)
Homo sapiens — UniProt Q9Y2S6
Data last refreshed: (UniProt release unknown)
Key facts
Translation machinery-associated protein 7 (TMA7) is a protein from Homo sapiens identified by UniProt accession Q9Y2S6, 64 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q9Y2S6; gene symbol TMA7.
- Organism: Homo sapiens.
- Length: 64 amino acids.
- Top disease associations (Open Targets): glomerular filtration rate, platelet count and HbA1c measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Translation machinery-associated protein 7 |
|---|---|
| UniProt accession | Q9Y2S6 |
| Gene | TMA7 |
| Organism | Homo sapiens |
| Length | 64 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- glomerular filtration rate · score 0.15
- platelet count · score 0.08
- HbA1c measurement · score 0.05
- bilirubin measurement · score 0.05
- alkaline phosphatase measurement · score 0.05
- age at first sexual intercourse measurement · score 0.03
- Immature Reticulocyte Fraction Measurement · score 0.02
- laryngeal squamous cell carcinoma · score 0.01
- neoplasm · score 0.01
- acute myeloid leukemia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2S6-F1 | alphafold | PREDICTED | 70.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2S6.
Amino-acid sequence (64 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMA7?
The strongest Open Targets associations for TMA7 are glomerular filtration rate, platelet count, HbA1c measurement, bilirubin measurement and alkaline phosphatase measurement.
How long is the TMA7 protein?
The Homo sapiens TMA7 protein (UniProt Q9Y2S6) is 64 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2S6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2S6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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