G-protein coupled receptor 52 (GPR52)
Homo sapiens — UniProt Q9Y2T5
Data last refreshed: (UniProt release unknown)
Key facts
G-protein coupled receptor 52 (GPR52) is a protein from Homo sapiens identified by UniProt accession Q9Y2T5, 361 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.
- UniProt accession: Q9Y2T5; gene symbol GPR52.
- Organism: Homo sapiens.
- Length: 361 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, Huntington disease and chronotype measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | G-protein coupled receptor 52 |
|---|---|
| UniProt accession | Q9Y2T5 |
| Gene | GPR52 |
| Organism | Homo sapiens |
| Length | 361 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (50)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.09
- Huntington disease · score 0.09
- chronotype measurement · score 0.07
- body height · score 0.06
- feeling tense measurement · score 0.06
- longevity · score 0.06
- sebaceous of Jadassohn nevus · score 0.05
- musculoskeletal system disease · score 0.05
- connective tissue disease · score 0.05
- actinic keratosis · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2T5-F1 | alphafold | PREDICTED | 81.77 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2T5.
Amino-acid sequence (361 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GPR52?
The strongest Open Targets associations for GPR52 are Red cell distribution width, Huntington disease, chronotype measurement, body height and feeling tense measurement.
How long is the GPR52 protein?
The Homo sapiens GPR52 protein (UniProt Q9Y2T5) is 361 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2T5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2T5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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