Retinal homeobox protein Rx (RAX)
Homo sapiens — UniProt Q9Y2V3
Data last refreshed: (UniProt release unknown)
Key facts
Retinal homeobox protein Rx (RAX) is a protein from Homo sapiens identified by UniProt accession Q9Y2V3, 346 residues long. MolForge cross-references it against 0 known binders and 106 disease associations.
- UniProt accession: Q9Y2V3; gene symbol RAX.
- Organism: Homo sapiens.
- Length: 346 amino acids.
- Top disease associations (Open Targets): Isolated anophthalmia - microphthalmia, microphthalmia and nanophthalmia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Retinal homeobox protein Rx |
|---|---|
| UniProt accession | Q9Y2V3 |
| Gene | RAX |
| Organism | Homo sapiens |
| Length | 346 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (106)
Diseases linked to this target (Open Targets).
- Isolated anophthalmia - microphthalmia · score 0.76
- microphthalmia · score 0.56
- nanophthalmia · score 0.38
- microphthalmia, isolated, with coloboma · score 0.37
- macula measurement · score 0.23
- PHF-tau measurement · score 0.20
- genetic disorder · score 0.19
- anophthalmia-microphthalmia syndrome · score 0.17
- microphthalmia, isolated, with coloboma 10 · score 0.07
- Microphthalmia - ankyloblepharon - intellectual disability · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2V3-F1 | alphafold | PREDICTED | 63.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2V3.
Amino-acid sequence (346 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RAX?
The strongest Open Targets associations for RAX are Isolated anophthalmia - microphthalmia, microphthalmia, nanophthalmia, microphthalmia, isolated, with coloboma and macula measurement.
How long is the RAX protein?
The Homo sapiens RAX protein (UniProt Q9Y2V3) is 346 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2V3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2V3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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