Ubiquitin-conjugating enzyme E2 D4 (UBE2D4)
Homo sapiens — UniProt Q9Y2X8
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquitin-conjugating enzyme E2 D4 (UBE2D4) is a protein from Homo sapiens identified by UniProt accession Q9Y2X8, 147 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q9Y2X8; gene symbol UBE2D4.
- Organism: Homo sapiens.
- Length: 147 amino acids.
- Top disease associations (Open Targets): vitamin D measurement, pancreatic adenocarcinoma and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquitin-conjugating enzyme E2 D4 |
|---|---|
| UniProt accession | Q9Y2X8 |
| Gene | UBE2D4 |
| Organism | Homo sapiens |
| Length | 147 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- vitamin D measurement · score 0.26
- pancreatic adenocarcinoma · score 0.18
- mean platelet volume · score 0.12
- reticulocyte measurement · score 0.10
- diabetes mellitus · score 0.04
- reticulocyte count · score 0.04
- Sepsis · score 0.01
- lung adenocarcinoma · score 0.01
- cancer · score 0.01
- calf circumference measurement · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2X8-F1 | alphafold | PREDICTED | 96.32 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2X8.
Amino-acid sequence (147 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UBE2D4?
The strongest Open Targets associations for UBE2D4 are vitamin D measurement, pancreatic adenocarcinoma, mean platelet volume, reticulocyte measurement and diabetes mellitus.
How long is the UBE2D4 protein?
The Homo sapiens UBE2D4 protein (UniProt Q9Y2X8) is 147 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2X8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2X8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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