Zinc finger and BTB domain-containing protein 32 (ZBTB32)
Homo sapiens — UniProt Q9Y2Y4
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger and BTB domain-containing protein 32 (ZBTB32) is a protein from Homo sapiens identified by UniProt accession Q9Y2Y4, 487 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.
- UniProt accession: Q9Y2Y4; gene symbol ZBTB32.
- Organism: Homo sapiens.
- Length: 487 amino acids.
- Top disease associations (Open Targets): white matter microstructure measurement, brain measurement and neuroimaging measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger and BTB domain-containing protein 32 |
|---|---|
| UniProt accession | Q9Y2Y4 |
| Gene | ZBTB32 |
| Organism | Homo sapiens |
| Length | 487 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (63)
Diseases linked to this target (Open Targets).
- white matter microstructure measurement · score 0.15
- brain measurement · score 0.15
- neuroimaging measurement · score 0.15
- eosinophil percentage of leukocytes · score 0.14
- eosinophil count · score 0.11
- infection · score 0.08
- infect · score 0.08
- self reported educational attainment · score 0.08
- IGF-1 measurement · score 0.07
- Red cell distribution width · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2Y4-F1 | alphafold | PREDICTED | 56.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2Y4.
Amino-acid sequence (487 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZBTB32?
The strongest Open Targets associations for ZBTB32 are white matter microstructure measurement, brain measurement, neuroimaging measurement, eosinophil percentage of leukocytes and eosinophil count.
How long is the ZBTB32 protein?
The Homo sapiens ZBTB32 protein (UniProt Q9Y2Y4) is 487 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2Y4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2Y4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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