Transmembrane protein 98 (TMEM98)
Homo sapiens — UniProt Q9Y2Y6
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 98 (TMEM98) is a protein from Homo sapiens identified by UniProt accession Q9Y2Y6, 226 residues long. MolForge cross-references it against 0 known binders and 125 disease associations.
- UniProt accession: Q9Y2Y6; gene symbol TMEM98.
- Organism: Homo sapiens.
- Length: 226 amino acids.
- Top disease associations (Open Targets): microphthalmia, nanophthalmia and serum gamma-glutamyl transferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 98 |
|---|---|
| UniProt accession | Q9Y2Y6 |
| Gene | TMEM98 |
| Organism | Homo sapiens |
| Length | 226 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (125)
Diseases linked to this target (Open Targets).
- microphthalmia · score 0.69
- nanophthalmia · score 0.68
- serum gamma-glutamyl transferase measurement · score 0.22
- refractive error · score 0.21
- Abnormality of refraction · score 0.21
- Red cell distribution width · score 0.19
- Myopia · score 0.19
- genetic disorder · score 0.18
- age at onset · score 0.16
- refractive error measurement · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2Y6-F1 | alphafold | PREDICTED | 71.99 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2Y6.
Amino-acid sequence (226 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM98?
The strongest Open Targets associations for TMEM98 are microphthalmia, nanophthalmia, serum gamma-glutamyl transferase measurement, refractive error and Abnormality of refraction.
How long is the TMEM98 protein?
The Homo sapiens TMEM98 protein (UniProt Q9Y2Y6) is 226 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2Y6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2Y6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.