Krueppel-like factor 13 (KLF13)
Homo sapiens — UniProt Q9Y2Y9
Data last refreshed: (UniProt release unknown)
Key facts
Krueppel-like factor 13 (KLF13) is a protein from Homo sapiens identified by UniProt accession Q9Y2Y9, 288 residues long. MolForge cross-references it against 0 known binders and 315 disease associations.
- UniProt accession: Q9Y2Y9; gene symbol KLF13.
- Organism: Homo sapiens.
- Length: 288 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, BMI-adjusted waist-hip ratio and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Krueppel-like factor 13 |
|---|---|
| UniProt accession | Q9Y2Y9 |
| Gene | KLF13 |
| Organism | Homo sapiens |
| Length | 288 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (315)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.53
- BMI-adjusted waist-hip ratio · score 0.53
- Red cell distribution width · score 0.52
- mean corpuscular hemoglobin · score 0.50
- mean corpuscular hemoglobin concentration · score 0.48
- sex hormone-binding globulin measurement · score 0.48
- waist-hip ratio · score 0.47
- high density lipoprotein cholesterol measurement · score 0.47
- BMI-adjusted hip circumference · score 0.46
- neurodegenerative disease · score 0.46
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2Y9-F1 | alphafold | PREDICTED | 58.07 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2Y9.
Amino-acid sequence (288 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KLF13?
The strongest Open Targets associations for KLF13 are mean corpuscular volume, BMI-adjusted waist-hip ratio, Red cell distribution width, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration.
How long is the KLF13 protein?
The Homo sapiens KLF13 protein (UniProt Q9Y2Y9) is 288 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2Y9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2Y9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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