Protein SGT1 homolog (SUGT1)
Homo sapiens — UniProt Q9Y2Z0
Data last refreshed: (UniProt release unknown)
Key facts
Protein SGT1 homolog (SUGT1) is a protein from Homo sapiens identified by UniProt accession Q9Y2Z0, 365 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q9Y2Z0; gene symbol SUGT1.
- Organism: Homo sapiens.
- Length: 365 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, lung adenocarcinoma and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein SGT1 homolog |
|---|---|
| UniProt accession | Q9Y2Z0 |
| Gene | SUGT1 |
| Organism | Homo sapiens |
| Length | 365 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- lung adenocarcinoma · score 0.21
- Red cell distribution width · score 0.18
- cutaneous melanoma · score 0.10
- cancer · score 0.07
- neoplasm · score 0.05
- body mass index · score 0.03
- Ewing sarcoma · score 0.02
- rhabdomyosarcoma · score 0.02
- fracture of pelvis · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y2Z0-F1 | alphafold | PREDICTED | 76.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y2Z0.
Amino-acid sequence (365 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SUGT1?
The strongest Open Targets associations for SUGT1 are neurodegenerative disease, lung adenocarcinoma, Red cell distribution width, cutaneous melanoma and cancer.
How long is the SUGT1 protein?
The Homo sapiens SUGT1 protein (UniProt Q9Y2Z0) is 365 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y2Z0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y2Z0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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