N-acetylglucosamine-6-phosphate deacetylase (AMDHD2)
Homo sapiens — UniProt Q9Y303
Data last refreshed: (UniProt release unknown)
Key facts
N-acetylglucosamine-6-phosphate deacetylase (AMDHD2) is a protein from Homo sapiens identified by UniProt accession Q9Y303, 409 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q9Y303; gene symbol AMDHD2.
- Organism: Homo sapiens.
- Length: 409 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cystatin C measurement and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | N-acetylglucosamine-6-phosphate deacetylase |
|---|---|
| UniProt accession | Q9Y303 |
| Gene | AMDHD2 |
| Organism | Homo sapiens |
| Length | 409 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.31
- cystatin C measurement · score 0.12
- body height · score 0.04
- sitting height measurement · score 0.04
- body fat percentage · score 0.03
- fat body mass · score 0.02
- body mass index · score 0.02
- infect · score 0.00
- neoplasm · score 0.00
- infection · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y303-F1 | alphafold | PREDICTED | 94.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y303.
Amino-acid sequence (409 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AMDHD2?
The strongest Open Targets associations for AMDHD2 are neurodegenerative disease, cystatin C measurement, body height, sitting height measurement and body fat percentage.
How long is the AMDHD2 protein?
The Homo sapiens AMDHD2 protein (UniProt Q9Y303) is 409 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y303 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y303 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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