Protein AAR2 homolog (AAR2)
Homo sapiens — UniProt Q9Y312
Data last refreshed: (UniProt release unknown)
Key facts
Protein AAR2 homolog (AAR2) is a protein from Homo sapiens identified by UniProt accession Q9Y312, 384 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q9Y312; gene symbol AAR2.
- Organism: Homo sapiens.
- Length: 384 amino acids.
- Top disease associations (Open Targets): Patent foramen ovale, ventricular septal defect and cerebellar malformation.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein AAR2 homolog |
|---|---|
| UniProt accession | Q9Y312 |
| Gene | AAR2 |
| Organism | Homo sapiens |
| Length | 384 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- Patent foramen ovale · score 0.26
- ventricular septal defect · score 0.26
- cerebellar malformation · score 0.26
- Global developmental delay · score 0.26
- Hypoplasia of the corpus callosum · score 0.26
- Microcephaly · score 0.26
- body mass index · score 0.07
- body height · score 0.07
- hair color · score 0.06
- cancer · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y312-F1 | alphafold | PREDICTED | 89.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y312.
Amino-acid sequence (384 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AAR2?
The strongest Open Targets associations for AAR2 are Patent foramen ovale, ventricular septal defect, cerebellar malformation, Global developmental delay and Hypoplasia of the corpus callosum.
How long is the AAR2 protein?
The Homo sapiens AAR2 protein (UniProt Q9Y312) is 384 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y312 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y312 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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