Dehydrogenase/reductase SDR family member 7 (DHRS7)
Homo sapiens — UniProt Q9Y394
Data last refreshed: (UniProt release unknown)
Key facts
Dehydrogenase/reductase SDR family member 7 (DHRS7) is a protein from Homo sapiens identified by UniProt accession Q9Y394, 339 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q9Y394; gene symbol DHRS7.
- Organism: Homo sapiens.
- Length: 339 amino acids.
- Top disease associations (Open Targets): mean platelet volume, age-related hearing impairment and calcium measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dehydrogenase/reductase SDR family member 7 |
|---|---|
| UniProt accession | Q9Y394 |
| Gene | DHRS7 |
| Organism | Homo sapiens |
| Length | 339 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.27
- age-related hearing impairment · score 0.21
- calcium measurement · score 0.18
- neoplasm · score 0.08
- cup-to-disc ratio measurement · score 0.06
- response to allogeneic hematopoietic stem cell transplant · score 0.04
- mortality · score 0.04
- donor genotype effect measurement · score 0.04
- uric acid measurement · score 0.03
- cancer · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y394-F1 | alphafold | PREDICTED | 94.38 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y394.
Amino-acid sequence (339 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DHRS7?
The strongest Open Targets associations for DHRS7 are mean platelet volume, age-related hearing impairment, calcium measurement, neoplasm and cup-to-disc ratio measurement.
How long is the DHRS7 protein?
The Homo sapiens DHRS7 protein (UniProt Q9Y394) is 339 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y394 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y394 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.