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Probable U3 small nucleolar RNA-associated protein 11 (UTP11)

Homo sapiens — UniProt Q9Y3A2

Gene: UTP11Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Probable U3 small nucleolar RNA-associated protein 11 (UTP11) is a protein from Homo sapiens identified by UniProt accession Q9Y3A2, 253 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.

  • UniProt accession: Q9Y3A2; gene symbol UTP11.
  • Organism: Homo sapiens.
  • Length: 253 amino acids.
  • Top disease associations (Open Targets): smoking status measurement, urate measurement and bone density.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProbable U3 small nucleolar RNA-associated protein 11
UniProt accessionQ9Y3A2
GeneUTP11
OrganismHomo sapiens
Length253 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (42)

Diseases linked to this target (Open Targets).

  • smoking status measurement · score 0.12
  • urate measurement · score 0.11
  • bone density · score 0.11
  • rheumatoid arthritis · score 0.11
  • hypothyroidism · score 0.10
  • age at menarche · score 0.09
  • Thyroid preparation use measurement · score 0.08
  • thyroid disease · score 0.08
  • serum non-albumin protein measurement · score 0.08
  • cancer · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9Y3A2-F1alphafoldPREDICTED91.15—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3A2.

Amino-acid sequence (253 residues)

MAAAFRKAAK SRQREHRERS QPGFRKHLGL LEKKKDYKLR ADDYRKKQEY LKALRKKALE KNPDEFYYKM TRVKLQDGVH IIKETKEEVT PEQLKLMRTQ DVKYIEMKRV AEAKKIERLK SELHLLDFQG KQQNKHVFFF DTKKEVEQFD VATHLQTAPE LVDRVFNRPR IETLQKEKVK GVTNQTGLKR IAKERQKQYN CLTQRIEREK KLFVIAQKIQ TRKDLMDKTQ KVKVKKETVN SPAIYKFQSR RKR

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with UTP11?

The strongest Open Targets associations for UTP11 are smoking status measurement, urate measurement, bone density, rheumatoid arthritis and hypothyroidism.

How long is the UTP11 protein?

The Homo sapiens UTP11 protein (UniProt Q9Y3A2) is 253 amino acids long.

Browse: Targets: U · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9Y3A2
GeneUTP11
OrganismHomo sapiens
Length253
Binders0
Diseases42
View on UniProt