MOB-like protein phocein (MOB4)
Homo sapiens — UniProt Q9Y3A3
Data last refreshed: (UniProt release unknown)
Key facts
MOB-like protein phocein (MOB4) is a protein from Homo sapiens identified by UniProt accession Q9Y3A3, 225 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.
- UniProt accession: Q9Y3A3; gene symbol MOB4.
- Organism: Homo sapiens.
- Length: 225 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, schizophrenia and autism spectrum disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | MOB-like protein phocein |
|---|---|
| UniProt accession | Q9Y3A3 |
| Gene | MOB4 |
| Organism | Homo sapiens |
| Length | 225 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (50)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- schizophrenia · score 0.22
- autism spectrum disorder · score 0.18
- chronotype measurement · score 0.17
- bipolar disorder · score 0.16
- obsessive-compulsive disorder · score 0.15
- unipolar depression · score 0.15
- Tourette syndrome · score 0.15
- attention deficit hyperactivity disorder · score 0.15
- anorexia nervosa · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3A3-F1 | alphafold | PREDICTED | 90.80 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3A3.
Amino-acid sequence (225 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MOB4?
The strongest Open Targets associations for MOB4 are neurodegenerative disease, schizophrenia, autism spectrum disorder, chronotype measurement and bipolar disorder.
How long is the MOB4 protein?
The Homo sapiens MOB4 protein (UniProt Q9Y3A3) is 225 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3A3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3A3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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