Ribosomal RNA-processing protein 7 homolog A (RRP7A)
Homo sapiens — UniProt Q9Y3A4
Data last refreshed: (UniProt release unknown)
Key facts
Ribosomal RNA-processing protein 7 homolog A (RRP7A) is a protein from Homo sapiens identified by UniProt accession Q9Y3A4, 280 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q9Y3A4; gene symbol RRP7A.
- Organism: Homo sapiens.
- Length: 280 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Microcephaly and microcephaly.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ribosomal RNA-processing protein 7 homolog A |
|---|---|
| UniProt accession | Q9Y3A4 |
| Gene | RRP7A |
| Organism | Homo sapiens |
| Length | 280 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.42
- Microcephaly · score 0.19
- microcephaly · score 0.18
- apolipoprotein A 1 measurement · score 0.17
- PHF-tau measurement · score 0.03
- mean platelet volume · score 0.02
- hepatocellular carcinoma · score 0.01
- colon carcinoma · score 0.00
- Neurodevelopmental disorder · score 0.00
- amebiasis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3A4-F1 | alphafold | PREDICTED | 79.45 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3A4.
Amino-acid sequence (280 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RRP7A?
The strongest Open Targets associations for RRP7A are neurodegenerative disease, Microcephaly, microcephaly, apolipoprotein A 1 measurement and PHF-tau measurement.
How long is the RRP7A protein?
The Homo sapiens RRP7A protein (UniProt Q9Y3A4) is 280 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3A4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3A4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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