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PRELI domain containing protein 3B (PRELID3B)

Homo sapiens — UniProt Q9Y3B1

Gene: PRELID3BHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

PRELI domain containing protein 3B (PRELID3B) is a protein from Homo sapiens identified by UniProt accession Q9Y3B1, 194 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

  • UniProt accession: Q9Y3B1; gene symbol PRELID3B.
  • Organism: Homo sapiens.
  • Length: 194 amino acids.
  • Top disease associations (Open Targets): platelet component distribution width, mean platelet volume and platelet count.
  • 3D structure: AlphaFold model available.

Target properties

Protein namePRELI domain containing protein 3B
UniProt accessionQ9Y3B1
GenePRELID3B
OrganismHomo sapiens
Length194 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (41)

Diseases linked to this target (Open Targets).

  • platelet component distribution width · score 0.30
  • mean platelet volume · score 0.27
  • platelet count · score 0.23
  • obesity · score 0.11
  • diabetes mellitus · score 0.08
  • cancer · score 0.08
  • neoplasm · score 0.08
  • type 2 diabetes mellitus · score 0.08
  • systolic blood pressure · score 0.06
  • metabolite measurement · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9Y3B1-F1alphafoldPREDICTED82.06—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3B1.

Amino-acid sequence (194 residues)

MKIWTSEHVF DHPWETVTTA AMQKYPNPMN PSVVGVDVLD RHIDPSGKLH SHRLLSTEWG LPSIVKSLIG AARTKTYVQE HSVVDPVEKT MELKSTNISF TNMVSVDERL IYKPHPQDPE KTVLTQEAII TVKGVSLSSY LEGLMASTIS SNASKGREAM EWVIHKLNAE IEELTASARG TIRTPMAAAA FAEK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with PRELID3B?

The strongest Open Targets associations for PRELID3B are platelet component distribution width, mean platelet volume, platelet count, obesity and diabetes mellitus.

How long is the PRELID3B protein?

The Homo sapiens PRELID3B protein (UniProt Q9Y3B1) is 194 amino acids long.

Browse: Targets: P · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9Y3B1
GenePRELID3B
OrganismHomo sapiens
Length194
Binders0
Diseases41
View on UniProt