Large ribosomal subunit protein uL11m (MRPL11)
Homo sapiens — UniProt Q9Y3B7
Data last refreshed: (UniProt release unknown)
Key facts
Large ribosomal subunit protein uL11m (MRPL11) is a protein from Homo sapiens identified by UniProt accession Q9Y3B7, 192 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q9Y3B7; gene symbol MRPL11.
- Organism: Homo sapiens.
- Length: 192 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, erythrocyte count and diet measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Large ribosomal subunit protein uL11m |
|---|---|
| UniProt accession | Q9Y3B7 |
| Gene | MRPL11 |
| Organism | Homo sapiens |
| Length | 192 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.48
- erythrocyte count · score 0.08
- diet measurement · score 0.05
- antisocial behaviour measurement · score 0.03
- substance abuse · score 0.03
- attention deficit hyperactivity disorder · score 0.03
- risk-taking behaviour · score 0.03
- blood phosphate measurement · score 0.03
- high density lipoprotein cholesterol measurement · score 0.03
- IGF-1 measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3B7-F1 | alphafold | PREDICTED | 83.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3B7.
Amino-acid sequence (192 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPL11?
The strongest Open Targets associations for MRPL11 are neurodegenerative disease, erythrocyte count, diet measurement, antisocial behaviour measurement and substance abuse.
How long is the MRPL11 protein?
The Homo sapiens MRPL11 protein (UniProt Q9Y3B7) is 192 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3B7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3B7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.